Successful application of virtual screening and molecular dynamics simulations against antimalarial molecular targets
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چکیده
منابع مشابه
Successful application of virtual screening and molecular dynamics simulations against antimalarial molecular targets
The main challenge in the control of malaria has been the emergence of drug-resistant parasites. The presence of drug-resistant Plasmodium sp. has raised the need for new antimalarial drugs. Molecular modelling techniques have been used as tools to develop new drugs. In this study, we employed virtual screening of a pyrazol derivative (Tx001) against four malaria targets: plasmepsin-IV, plasmep...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2016
ISSN: 1678-8060,0074-0276
DOI: 10.1590/0074-02760160207